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EMMERSON2 1New Jersey Health Care System, East Orange, New Jersey, USA 2University of Queensland, Brisbane, Queensland, Australia Introduction ___________________________________________________________495 Handling of lead in the human body _____________________________________ 496 Exposure, absorption, elimination and toxicity 496 Modifying factors 496 Acute lead nephropathy_________________________________________________497 Chronic renal disease due to lead ________________________________________ 497 Chronic lead nephropathy in Queensland 498 Moonshine 499 Association with gout 500 Association with hypertension 500 Occupational lead nephropathy 501 Assessing the body burden 502 Treatment _____________________________________________________________503 References _____________________________________________________________ 503 Introduction Because of its stability and malleability, lead has been used by man for millennia.
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